Bicarbonate Ion → 7-Bromo-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
Reaction equation
[Br:1][c:2]1[n:3][c:4]([NH:15][CH:16]2[CH2:17][CH2:18][CH:19]([O:22][CH3:23])[CH2:20][CH2:21]2)[c:5]([NH:8][CH2:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])[n:6][cH:7]1.[C:33](=[O:34])([OH:35])[O-:36].[CH3:24][OH:25].[F:26][C:27]([F:28])([F:29])[C:30]([OH:31])=[O:32].[Na+:37].[OH2:38]>>[Br:1][c:2]1[n:3][c:4]2[c:5]([n:6][cH:7]1)[NH:8][CH2:9][C:10](=[O:11])[N:15]2[CH:16]1[CH2:17][CH2:18][CH:19]([O:22][CH3:23])[CH2:20][CH2:21]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d6242447f2214e909fd9988e9be3d859
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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