HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20468376, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(o-Fluorobenzoyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane | HCID 20468333 | — |
| Reactant | Sodium bis(2-methoxyethoxy)aluminiumhydride | HCID 21584525 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20468376 | HCID 20468376 | — |
Reaction Steps
A 13.9 g portion of 3-(o-fluorobenzoyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane is reacted as described in Example 19 with 50 ml of sodium bis(2-methoxyethoxy)aluminum hydride (70% benzene solution) yielding a light yellow oil. This base is treated with ethanolic hydrochloric acid and ether to give the hydrochloride as a white solid, mp 204°-206° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04131611 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-e599dc8fb1914e0888bfb5af3bfef33f |
| Source note | uspto-grants-1978_12 |