Ammonia → 5-(3-Bromo-5-nitrophenyl)-5-methyl-2,6-dihydro-1,4-oxazin-3-amine

HRID 662875Notes

Reaction equation

HRID 662875 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:11]2([CH3:18])[NH:12][C:13](=[S:17])[CH2:14][O:15][CH2:16]2)[cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1.[C:19]([O:20][OH:21])([CH3:22])([CH3:23])[CH3:24].[CH3:35][OH:36].[NH3:26].[NH3:34].[Na+:27].[Na+:28].[O-:29][S:30]([O-:31])(=[S:32])=[O:33].[OH-:25]>>[Br:1][c:2]1[cH:3][c:4]([C:11]2([CH3:18])[N:12]=[C:13]([NH2:26])[CH2:14][O:15][CH2:16]2)[cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1

Participants

8

Reactant 7

HCID 222Ammonia2×HCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 1084Thiosulfate ionHCID 6410tert-Butyl hydroperoxideHCID 870965245-(3-Bromo-5-nitrophenyl)-5-methylmorpholine-3-thione

Product 1

HCID 676094625-(3-Bromo-5-nitrophenyl)-5-methyl-2,6-dihydro-1,4-oxazin-3-amine

Sources & evidence

ORD record
ord-8c290fbae6c2437ebef193c1bc942419
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…