Chlorotrimethylsilane → 8-(4-Iodo-phenyl)-1,4-dioxa-spiro[4.5]decan-8-ol
Reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:25][Si:26]([Cl:27])([CH3:28])[CH3:29].[CH3:9][CH2:10][CH2:11][CH2:12][Li:13].[I:1][c:2]1[cH:3][cH:4][c:5]([I:8])[cH:6][cH:7]1.[O:14]1[CH2:15][CH2:16][O:17][C:18]12[CH2:19][CH2:20][C:21](=[O:24])[CH2:22][CH2:23]2>>[c:2]1([C:21]2([OH:24])[CH2:20][CH2:19][C:18]3([O:14][CH2:15][CH2:16][O:17]3)[CH2:23][CH2:22]2)[cH:3][cH:4][c:5]([I:8])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-060f1322012b4968afffb608d800bd74
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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