Sodium ion → 1-((2-(isoquinolin-5-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)-N,N-dimethylpiperidin-4-amine
Reaction equation
[CH3:87][C:88]#[N:89].[Cl:1][c:2]1[n:3][c:4]([N:21]2[CH2:22][CH2:23][O:24][CH2:25][CH2:26]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([N:18]([CH3:19])[CH3:20])[CH2:16][CH2:17]1)[s:10]2.[Na+:40].[Na+:41].[O-:42][C:43](=[O:44])[O-:45].[Pd:46]([Cl:47])[Cl:48].[c:49]1([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:63][cH:64][cH:65][cH:66][cH:67]1.[c:68]1([P:69]([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[cH:82][cH:83][cH:84][cH:85][cH:86]1.[cH:27]1[n:28][cH:29][cH:30][c:31]2[c:32]([B:37]([OH:38])[OH:39])[cH:33][cH:34][cH:35][c:36]12>>[c:2]1(-[c:32]2[c:31]3[cH:30][cH:29][n:28][cH:27][c:36]3[cH:35][cH:34][cH:33]2)[n:3][c:4]([N:21]2[CH2:22][CH2:23][O:24][CH2:25][CH2:26]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([N:18]([CH3:19])[CH3:20])[CH2:16][CH2:17]1)[s:10]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e9046c95edc9410f8a3769240ad6b784
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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