2,2-Difluoroethyl trifluoromethanesulfonate → 5-(2,2-Difluoro-ethoxy)-pyridine-2-carboxylic acid
Reaction equation
[CH3:15][O:16][C:17]([c:18]1[cH:19][cH:20][c:21]([OH:22])[cH:23][n:24]1)=[O:25].[CH3:38][O:39][C:40](=[O:41])[c:42]1[n:43][cH:44][c:45]([O:48][CH2:49][CH:50]([F:51])[F:52])[cH:46][cH:47]1.[CH:1]1([CH2:2][O:3][c:4]2[cH:5][cH:6][c:7]([C:8]([OH:9])=[O:10])[n:11][cH:12]2)[CH2:13][CH2:14]1.[S:26]([O:27][CH2:28][CH:29]([F:30])[F:31])([C:32]([F:33])([F:34])[F:35])(=[O:36])=[O:37]>>[O:39]=[C:40]([OH:41])[c:42]1[n:43][cH:44][c:45]([O:48][CH2:49][CH:50]([F:51])[F:52])[cH:46][cH:47]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0c96ffb87bf34d9d831600a7d53f808a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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