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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 663259Generated: October 29, 2026

2,2-Difluoroethyl trifluoromethanesulfonate → 5-(2,2-Difluoro-ethoxy)-pyridine-2-carboxylic acid

https://huagongshe.com/reaction/663259

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Difluoroethyl trifluoromethanesulfonateHCID 2774089—
ReactantMethyl 5-hydroxypyridine-2-carboxylateHCID 4715126—
Reactant5-(2,2-Difluoro-ethoxy)-pyridine-2-carboxylic acid methyl esterHCID 57827763—
Reactant5-(Cyclopropylmethoxy)pyridine-2-carboxylic acidHCID 66691895—
Product5-(2,2-Difluoro-ethoxy)-pyridine-2-carboxylic acidHCID 57475872—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-0c96ffb87bf34d9d831600a7d53f808a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)