Pyridine → 3-(4-amino-phenyl)-5-chloro-3-methyl-7-(4-methyl-piperazine-1-yl)-1H-quinoline-2,4-dione

HRID 663552Notes

Reaction equation

HRID 663552 reaction equation
[CH3:23][N:24]1[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([CH3:22])[C:9](=[O:21])[NH:10][c:11]3[cH:12][c:13]([Cl:20])[cH:14][c:15]([Cl:19])[c:16]3[C:17]2=[O:18])[cH:6][cH:7]1.[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([CH3:22])[C:9](=[O:21])[NH:10][c:11]3[cH:12][c:13]([N:27]4[CH2:26][CH2:25][N:24]([CH3:23])[CH2:29][CH2:28]4)[cH:14][c:15]([Cl:19])[c:16]3[C:17]2=[O:18])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 531671-MethylpiperazineHCID 115735593-(4-amino-phenyl)-5,7-dichloro-3-methyl-1H-quinoline-2,4-dione

Product 1

HCID 116756863-(4-amino-phenyl)-5-chloro-3-methyl-7-(4-methyl-piperazine-1-yl)-1H-quinoline-2,4-dione

Sources & evidence

ORD record
ord-e26822ab98cd486f98d70cf34f14b07c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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