Methyl Acrylate → tert-butyl 7-(3-methoxy-3-oxoprop-1-enyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-1'-carboxylate

HRID 663650Notes

Reaction equation

HRID 663650 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([O:12][c:13]3[cH:14][c:15]([Br:22])[cH:16][cH:17][c:18]3[C:19](=[O:21])[CH2:20]2)[CH2:23][CH2:24]1.[C:25]([CH:26]=[CH2:27])(=[O:28])[O:29][CH3:30].[CH3:31][O:32][C:33](=[O:34])[CH:35]=[CH:36][c:37]1[cH:38][c:39]2[c:40]([cH:41][cH:42]1)[O:43][C:44]1([CH2:45][CH2:46][NH:47][CH2:48][CH2:49]1)[CH2:50][C:51]2=[O:52]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([O:12][c:13]3[cH:14][c:15]([CH:27]=[CH:26][C:25](=[O:28])[O:29][CH3:30])[cH:16][cH:17][c:18]3[C:19](=[O:21])[CH2:20]2)[CH2:23][CH2:24]1

Participants

4

Reactant 3

HCID 7294Methyl AcrylateHCID 27281806N-Boc-7-bromo-4-oxo-3,4-dihydro-1'H-spiro[chromene-2,4'-piperidine]HCID 66932212methyl 3-(4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)prop-2-enoate

Product 1

HCID 66932193tert-butyl 7-(3-methoxy-3-oxoprop-1-enyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-1'-carboxylate

Sources & evidence

ORD record
ord-25b612ab205740968b6f290362b5db8d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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