Dichloromethane → 4-{2-[2-(Benzyloxycarbonyl-methyl-amino)-propionylamino]-3-hydroxy-butyryl}-3-(6-fluoro-1H-indol-3-yl)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]2[CH:13]([CH:14]([c:16]3[cH:17][nH:18][c:19]4[cH:20][c:21]([F:25])[cH:22][cH:23][c:24]34)[CH2:15]1)[N:26]([C:29]([CH:30]([CH:31]([CH3:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37])[NH:38][C:39]([CH:40]([CH3:41])[N:42]([CH3:43])[C:44](=[O:45])[O:46][CH2:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1)=[O:54])=[O:55])[CH2:27][CH2:28]2.[Cl:63][CH2:64][Cl:65].[F:56][C:57]([F:58])([F:59])[C:60]([OH:61])=[O:62]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]2[CH:13]([CH:14]([c:16]3[cH:17][nH:18][c:19]4[cH:20][c:21]([F:25])[cH:22][cH:23][c:24]34)[CH2:15]1)[N:26]([C:29]([CH:30]([CH:31]([CH3:32])[OH:33])[NH:38][C:39]([CH:40]([CH3:41])[N:42]([CH3:43])[C:44](=[O:45])[O:46][CH2:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1)=[O:54])=[O:55])[CH2:27][CH2:28]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2b63f410c508400a89752a17dff5e8b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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