Propionic anhydride → 2-(Dipropylamino)-4-phenoxy-1-butanol

HRID 66418Notes

Reaction equation

[CH2:1]([NH:4][CH:5]([CH2:8][CH2:9][O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH2:6][OH:7])[CH2:2][CH3:3].[C:17](OC(=O)CC)(=O)[CH2:18][CH3:19]>>[CH2:1]([N:4]([CH2:17][CH2:18][CH3:19])[CH:5]([CH2:8][CH2:9][O:10][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)[CH2:6][OH:7])[CH2:2][CH3:3]

Participants

Reactant 2

HCID 31263Propionic anhydride

HCID 22755021HCID 22755021, compound

Product 1

HCID 227550122-(Dipropylamino)-4-phenoxy-1-butanol

Procedure

2-(propylamino)-4-phenoxy-1-butanol, described in Example 6, with propionic anhydride, followed by reduction, gives 2-(dipropylamino)-4-phenoxy-1-butanol,

Sources & evidence

ORD record: ord-b4f0518543414ed2a8a8e5680b0de751
Source dataset: uspto-grants-1978_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04131745

Reaction notes

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