Diethylcarbamoyl chloride → 3-(5-Chloro-6-methyl-1H-benzoimidazol-2-yl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid diethylamide

HRID 664260Notes

Reaction equation

HRID 664260 reaction equation
[CH2:1]([CH3:2])[N:3]([C:4](=[O:5])[N:6]1[CH2:7][c:8]2[c:9]([nH:12][n:13][c:14]2-[c:15]2[n:16][c:17]3[c:18]([nH:19]2)[cH:20][c:21]([CH3:25])[c:22]([CH3:24])[cH:23]3)[CH2:10][CH2:11]1)[CH2:26][CH3:27].[CH2:48]([N:49]([CH2:50][CH3:51])[C:52]([Cl:53])=[O:54])[CH3:55].[CH:56]([c:57]1[c:58]2[c:59]([cH:60][cH:61][c:62]([C:63]#[N:64])[cH:65]2)[nH:66][n:67]1)=[O:68].[Cl:28][c:29]1[c:30]([CH3:31])[cH:32][c:33]2[nH:34][c:35](-[c:36]3[c:37]4[c:42]([nH:43][n:44]3)[CH2:41][CH2:40][NH:39][CH2:38]4)[n:45][c:46]2[cH:47]1>>[CH2:1]([CH3:2])[N:3]([C:4](=[O:5])[N:6]1[CH2:7][c:8]2[c:9]([nH:12][n:13][c:14]2-[c:15]2[n:16][c:17]3[c:18]([nH:19]2)[cH:20][c:21]([CH3:25])[c:22]([Cl:28])[cH:23]3)[CH2:10][CH2:11]1)[CH2:26][CH3:27]

Participants

5

Reactant 4

HCID 6916Diethylcarbamoyl chlorideHCID 1358046413-(5-chloro-6-methyl-1H-benzoimidazol-2-yl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridineHCID 1359320273-(5,6-Dimethyl-1H-benzoimidazol-2-yl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid diethylamideHCID 178509533HCID 178509533, compound

Product 1

HCID 1357507073-(5-Chloro-6-methyl-1H-benzoimidazol-2-yl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid diethylamide

Sources & evidence

ORD record
ord-fb380458a0dd43299ac310d3a4334e99
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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