4-Methoxy-3-nitrobenzaldehyde → (3-Ethoxy-4-methoxy-phenyl)-(4-methoxy-3-nitro-phenyl)-methanol

HRID 664291Notes

Reaction equation

HRID 664291 reaction equation
[CH2:24]([CH3:25])[O:26][c:27]1[cH:28][c:29]([Br:35])[cH:30][cH:31][c:32]1[O:33][CH3:34].[CH3:37][O:38][c:39]1[c:40]([N+:47](=[O:48])[O-:49])[cH:41][c:42]([CH:43]=[O:44])[cH:45][cH:46]1.[Mg:36].[NH2:1][c:2]1[cH:3][c:4]([C:5]([c:6]2[cH:7][cH:8][c:9]([O:10][CH3:11])[c:12]([O:13][CH3:14])[cH:15]2)=[CH:16][C:17]#[N:18])[cH:19][cH:20][c:21]1[O:22][CH3:23]>>[CH2:24]([CH3:25])[O:26][c:27]1[cH:28][c:29]([CH:43]([c:42]2[cH:41][c:40]([N+:47](=[O:48])[O-:49])[c:39]([O:38][CH3:37])[cH:46][cH:45]2)[OH:44])[cH:30][cH:31][c:32]1[O:33][CH3:34]

Participants

5

Reactant 4

HCID 7006084-Methoxy-3-nitrobenzaldehydeHCID 5462224MagnesiumHCID 217726904-Bromo-2-ethoxy-1-methoxybenzeneHCID 689400613-(3-Amino-4-methoxy-phenyl)-3-(3,4-dimethoxy-phenyl)-acrylonitrile

Product 1

HCID 69203000(3-Ethoxy-4-methoxy-phenyl)-(4-methoxy-3-nitro-phenyl)-methanol

Sources & evidence

ORD record
ord-ddd64567ca9d4c308d28dad98eaf3bc6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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