Dichloromethane → 4-{5-[(2-Phenyl-5-trifluoromethyl-oxazole-4-carbonyl)-amino]-pyridin-2-ylamino}-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:47][P+:48]([N:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1)([N:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1)[N:59]1[CH2:60][CH2:61][CH2:62][CH2:63]1.[C:19]([CH3:20])([CH3:21])([CH3:22])[O:23][C:24](=[O:25])[N:26]1[CH2:27][CH2:28][CH:29]([NH:32][c:33]2[n:34][cH:35][c:36]([NH2:39])[cH:37][cH:38]2)[CH2:30][CH2:31]1.[CH:64]([N:65]([CH:66]([CH3:67])[CH3:68])[CH2:69][CH3:70])([CH3:71])[CH3:72].[Cl:73][CH2:74][Cl:75].[P-:40]([F:41])([F:42])([F:43])([F:44])([F:45])[F:46].[c:1]1(-[c:7]2[o:8][c:9]([C:15]([F:16])([F:17])[F:18])[c:10]([C:12](=[O:13])[OH:14])[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[o:8][c:9]([C:15]([F:16])([F:17])[F:18])[c:10]([C:12](=[O:14])[NH:39][c:36]3[cH:35][n:34][c:33]([NH:32][CH:29]4[CH2:28][CH2:27][N:26]([C:24]([O:23][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:25])[CH2:31][CH2:30]4)[cH:38][cH:37]3)[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-73d85163378548bda8a1c2fbbfc3b3f7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…