Dimethylamine → Ethyl 2-(dimethylamino)-4-(trifluoromethyl)-5-oxazolecarboxylate

HRID 664523Notes

Reaction equation

HRID 664523 reaction equation
[C:14](=[O:15])([O-:16])[O-:17].[CH3:11][NH:12][CH3:13].[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[Cl:20][c:21]1[o:22][c:23]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[c:24]([C:26]([F:27])([F:28])[F:29])[n:25]1.[K+:18].[K+:19].[N+:1]([c:2]1[cH:3][cH:4][c:5]([OH:6])[cH:7][cH:8]1)([O-:9])=[O:10]>>[CH3:11][N:12]([CH3:13])[c:21]1[o:22][c:23]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[c:24]([C:26]([F:27])([F:28])[F:29])[n:25]1

Participants

7

Reactant 6

HCID 674DimethylamineHCID 813Potassium Cation2×HCID 9804-NitrophenolHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 12785855Ethyl 2-chloro-4-(trifluoromethyl)oxazole-5-carboxylate

Product 1

HCID 20064719Ethyl 2-(dimethylamino)-4-(trifluoromethyl)-5-oxazolecarboxylate

Sources & evidence

ORD record
ord-552fd298d208493c929df24cd89a0693
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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