Dichloromethane → 4-(6-Chlorobenzofuran-7-ylamino)-6-methoxy-7-(2-pyrrolidin-1-ylethoxy)quinazoline
Reaction equation
[CH2:64]([Cl:65])[Cl:66].[Cl:13][c:14]1[c:15]([NH:23][c:24]2[n:25][cH:26][n:27][c:28]3[cH:29][c:30]([OH:36])[c:31]([O:34][CH3:35])[cH:32][c:33]23)[c:16]2[c:17]([cH:18][cH:19][o:20]2)[cH:21][cH:22]1.[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[OH:37][CH2:38][CH2:39][N:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1.[c:45]1([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][cH:63]1>>[Cl:13][c:14]1[c:15]([NH:23][c:24]2[n:25][cH:26][n:27][c:28]3[cH:29][c:30]([O:36][CH2:38][CH2:39][N:40]4[CH2:41][CH2:42][CH2:43][CH2:44]4)[c:31]([O:34][CH3:35])[cH:32][c:33]23)[c:16]2[c:17]([cH:18][cH:19][o:20]2)[cH:21][cH:22]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b0353968abc54b8289dd9656422f884b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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