Water → 5-Chloro-N-[(5-chloro-2-thienyl)sulfonyl]-N-[4-(methyloxy)-1H-indazol-3-yl]-2-thiophenesulfonamide

HRID 664908Notes

Reaction equation

HRID 664908 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:7](=[O:8])(=[O:9])[N:10]([c:11]2[n:12][n:13]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[c:14]3[cH:15][cH:16][cH:17][c:18]([O:20][CH3:21])[c:19]23)[S:29](=[O:30])(=[O:31])[c:32]2[s:33][c:34]([Cl:37])[cH:35][cH:36]2)[s:6]1.[Cl:45][CH2:46][Cl:47].[F:38][C:39]([F:40])([F:41])[C:42]([OH:43])=[O:44].[OH2:48]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:7](=[O:8])(=[O:9])[N:10]([c:11]2[n:12][nH:13][c:14]3[cH:15][cH:16][cH:17][c:18]([O:20][CH3:21])[c:19]23)[S:29](=[O:30])(=[O:31])[c:32]2[s:33][c:34]([Cl:37])[cH:35][cH:36]2)[s:6]1

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 580544561,1-dimethylethyl 3-{bis[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazole-1-carboxylate

Product 1

HCID 580544545-Chloro-N-[(5-chloro-2-thienyl)sulfonyl]-N-[4-(methyloxy)-1H-indazol-3-yl]-2-thiophenesulfonamide

Sources & evidence

ORD record
ord-fd9d4cb252ab469a9a802995c998ffbd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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