Acetic Acid → 1-(3-Bromo-5-fluorophenyl)-4-cyclopropylpiperazine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[cH:5][c:6]([F:8])[cH:7]1.[CH2:15]([O:16][C:18]1([O:17][Si:21]([CH3:22])([CH3:23])[CH3:24])[CH2:19][CH2:20]1)[CH3:25].[CH3:26][C:27](=[O:28])[OH:29].[CH3:30][OH:31].[CH3:32][CH2:33][O:34][C:35]([CH3:36])=[O:37]>>[Br:1][c:2]1[cH:3][c:4]([N:9]2[CH2:10][CH2:11][N:12]([CH:18]3[CH2:19][CH2:20]3)[CH2:13][CH2:14]2)[cH:5][c:6]([F:8])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-235432fd63b44186b12e8177bdff1043
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…