Tetrahydrofuran → 4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile
Reaction equation
[CH2:26]([N+:27]([CH2:28][CH2:29][CH2:30][CH3:31])([CH2:32][CH2:33][CH2:34][CH3:35])[CH2:36][CH2:37][CH2:38][CH3:39])[CH2:40][CH2:41][CH3:42].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[Cl:1][c:2]1[c:3]2[cH:4][c:5]([CH:22]([F:23])[F:24])[n:6]([S:13]([c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)(=[O:20])=[O:21])[c:7]2[cH:8][cH:9][c:10]1[C:11]#[N:12].[F-:25]>>[Cl:1][c:2]1[c:3]2[cH:4][c:5]([CH:22]([F:23])[F:24])[nH:6][c:7]2[cH:8][cH:9][c:10]1[C:11]#[N:12]Participants
5
Sources & evidence
- ORD record
- ord-ce6fc67ab79a45ea90ce649091f2bc78
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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