Water → 3-Chloro-2-(4-chloro-3-isopropoxyphenyl)-5-trifluoromethylpyridine

HRID 665164Notes

Reaction equation

HRID 665164 reaction equation
[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[CH:20]([CH3:21])([CH3:22])[I:23].[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][c:14]([OH:19])[c:15]([Cl:18])[cH:16][cH:17]2)[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[OH2:24]>>[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][c:14]([O:19][CH:20]([CH3:21])[CH3:22])[c:15]([Cl:18])[cH:16][cH:17]2)[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

5

Reactant 4

HCID 962WaterHCID 6228DimethylformamideHCID 6362Isopropyl iodideHCID 190687593-Chloro-2-(4-chloro-3-hydroxyphenyl)5-trifluoromethylpyridine

Product 1

HCID 190687923-Chloro-2-(4-chloro-3-isopropoxyphenyl)-5-trifluoromethylpyridine

Sources & evidence

ORD record
ord-74f414d688d042f4b2f7d6373ec84e94
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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