HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline → 1-[2-Acetylthio-3-(1-methyl-4-pyrazolylcarbonyl)propionyl]-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline | HCID 145742 | — |
| Reactant | 1-[3-(1-methyl-4-pyrazolylcarbonyl)acryloyl]-L-proline | HCID 54006215 | — |
| Reactant | HCID 54556495 | HCID 54556495 | — |
| Reactant | HCID 178418634 | HCID 178418634 | — |
| Product | 1-[2-Acetylthio-3-(1-methyl-4-pyrazolylcarbonyl)propionyl]-L-proline | HCID 53840747 | — |
Reaction Steps
As for Example 29, 3-(1-methyl-4-pyrazolylcarbonyl)acrylic acid is coupled to L-proline and the resulting 1-[3-(1-methyl-4-pyrazolylcarbonyl)acryloyl]-L-proline is reacted with thioacetic acid to give the product of the Example as a glass.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04342691 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-d5519e15d0b24fb0a5ede94dfa48bb1f |
| Source note | uspto-grants-1982_08 |