Methanol → Methyl 4-[(2,6-diaminopyrimidin-4-yl)oxy]benzoate

HRID 665481Notes

Reaction equation

HRID 665481 reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[CH3:21][OH:22].[Cl:12][c:13]1[n:14][c:15]([NH2:20])[n:16][c:17]([NH2:19])[cH:18]1.[Cs+:33].[Cs+:34].[O:23]1[CH2:24][CH2:25][O:26][CH2:27][CH2:28]1.[OH:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1)[c:13]1[n:14][c:15]([NH2:20])[n:16][c:17]([NH2:19])[cH:18]1

Participants

7

Reactant 6

HCID 887MethanolHCID 7456MethylparabenHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 674322,4-Diamino-6-chloropyrimidineHCID 104967Cesium cation2×

Product 1

HCID 59135324Methyl 4-[(2,6-diaminopyrimidin-4-yl)oxy]benzoate

Sources & evidence

ORD record
ord-1c600553122d4ac5bcb197835c3b2309
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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