Ammonia → Tert-butyl 4-(aminomethyl)-3-methoxypiperidine-1-carboxylate

HRID 665576Notes

Reaction equation

HRID 665576 reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6]([O:7][CH2:12][CH:13]2[CH:14]([O:26][CH3:27])[CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]2)(=[O:8])=[O:9])[cH:10][cH:11]1.[NH3:28]>>[CH2:12]([CH:13]1[CH:14]([O:26][CH3:27])[CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]1)[NH2:28]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 8028TetrahydrofuranHCID 22708832Tert-butyl 3-methoxy-4-[(4-methylphenyl)sulfonyloxymethyl]piperidine-1-carboxylate

Product 1

HCID 22708830Tert-butyl 4-(aminomethyl)-3-methoxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-9504203343db4558ae0e8bf0ec7ed67c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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