Diisopropylamine → tert-butyl 3-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methylene)azetidine-1-carboxylate
Reaction equation
[C:37]([CH3:38])([CH3:39])([CH3:40])[O:41][C:42](=[O:43])[N:44]1[CH2:45][C:46](=[O:48])[CH2:47]1.[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:13][O:14][P:15](=[O:16])([O:17][CH3:18])[CH2:19][c:20]1[n:21]([CH3:36])[c:22]2[n:23][c:24]([Cl:35])[n:25][c:26]([N:29]3[CH2:30][CH2:31][O:32][CH2:33][CH2:34]3)[c:27]2[n:28]1.[CH3:8][CH2:9][CH2:10][CH2:11][Li:12].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7]>>[CH:19]([c:20]1[n:21]([CH3:36])[c:22]2[n:23][c:24]([Cl:35])[n:25][c:26]([N:29]3[CH2:30][CH2:31][O:32][CH2:33][CH2:34]3)[c:27]2[n:28]1)=[C:46]1[CH2:45][N:44]([C:42]([O:41][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:43])[CH2:47]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4bc27b8097864a49981a43646dee0082
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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