Dimethylformamide → [2-(4-Chloro-phenyl)-benzoimidazol-1-yl]-cyclohexyl-acetic acid ethyl ester

HRID 665790Notes

Reaction equation

HRID 665790 reaction equation
[C:17](=[O:18])([O-:19])[O-:20].[CH2:23]([CH3:24])[O:25][C:26]([CH:27]([CH:28]1[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1)[Br:34])=[O:35].[CH3:36][N:37]([CH3:38])[CH:39]=[O:40].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[nH:9][c:10]3[c:11]([n:12]2)[cH:13][cH:14][cH:15][cH:16]3)[cH:6][cH:7]1.[Cs+:21].[Cs+:22]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:27]([C:26]([O:25][CH2:23][CH3:24])=[O:35])[CH:28]2[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]2)[cH:13][cH:14][cH:15][cH:16]3)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 7594172-(4-Chlorophenyl)benzimidazoleHCID 2762757Ethyl 2-bromo-2-cyclohexylacetate

Product 1

HCID 66619211[2-(4-Chloro-phenyl)-benzoimidazol-1-yl]-cyclohexyl-acetic acid ethyl ester

Sources & evidence

ORD record
ord-07e52f11be4642d9ae7ead1ddbe6bf7c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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