Dimethylformamide → 4-Amino-3,5-difluorobenzonitrile

HRID 665893Notes

Reaction equation

HRID 665893 reaction equation
[Br:4][c:5]1[cH:6][c:7]([F:13])[c:8]([NH2:12])[c:9]([F:11])[cH:10]1.[Cu:1][C:2]#[N:3].[O:14]=[CH:15][N:16]([CH3:17])[CH3:18]>>[C:2](#[N:3])[c:5]1[cH:6][c:7]([F:13])[c:8]([NH2:12])[c:9]([F:11])[cH:10]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 6101914-Bromo-2,6-difluoroanilineHCID 178418546HCID 178418546, compound

Product 1

HCID 2804674-Amino-3,5-difluorobenzonitrile

Sources & evidence

ORD record
ord-0d7a01575abf49d1a71aad0e1eb027ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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