1-Methylpiperazine → [1-(2,5-Difluorobenzyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl]-(4-methylpiperazin-1-yl)methanone

HRID 665931Notes

Reaction equation

HRID 665931 reaction equation
[CH3:23][N:24]1[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]1.[F:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13]([C:15](=[O:16])[OH:17])[cH:14]3)[NH:8][CH2:9][CH2:10]2)[cH:18][c:19]([F:22])[cH:20][cH:21]1>>[F:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13]([C:15](=[O:17])[N:27]4[CH2:26][CH2:25][N:24]([CH3:23])[CH2:29][CH2:28]4)[cH:14]3)[NH:8][CH2:9][CH2:10]2)[cH:18][c:19]([F:22])[cH:20][cH:21]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 578860601-(2,5-Difluorobenzyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylic acid

Product 1

HCID 57886071[1-(2,5-Difluorobenzyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl]-(4-methylpiperazin-1-yl)methanone

Sources & evidence

ORD record
ord-3952ae987b72459ab50e4cdc8b8d34cf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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