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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 665986Generated: October 30, 2026

1-Butanol → 1-[5-Fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazine

https://huagongshe.com/reaction/665986

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-ButanolHCID 263—
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantBis(2-chloroethyl)amineHCID 9533—
ReactantCarbonate IonHCID 19660—
ReactantIodide IonHCID 30165—
Reactant5-Fluoro-2-(2,2,2-trifluoroethoxy)anilineHCID 17485413—
Product1-[5-Fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazineHCID 23447904—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-01bca063fbcb4d908f3456adb79b8e95
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)