1-Butanol → 1-[5-Fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazine
Reaction equation
[C:25](=[O:26])([O-:27])[O-:28].[CH2:31]([OH:32])[CH2:33][CH2:34][CH3:35].[Cl:16][CH2:17][CH2:18][NH:19][CH2:20][CH2:21][Cl:22].[ClH:15].[F:1][c:2]1[cH:3][cH:4][c:5]([O:9][CH2:10][C:11]([F:12])([F:13])[F:14])[c:6]([NH2:7])[cH:8]1.[I-:24].[K+:23].[K+:29].[K+:30]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:9][CH2:10][C:11]([F:12])([F:13])[F:14])[c:6]([N:7]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]2)[cH:8]1Participants
8
Sources & evidence
- ORD record
- ord-01bca063fbcb4d908f3456adb79b8e95
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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