Tetrafluoroborate → 5-bromo-6-chloro-N-(1-hydroxy-4-methylpentan-2-yl)pyridine-3-carboxamide

HRID 666207Notes

Reaction equation

HRID 666207 reaction equation
[B-:12]([F:13])([F:14])([F:15])[F:16].[Br:1][c:2]1[c:3]([Cl:11])[n:4][cH:5][c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[NH2:43][CH:44]([CH2:45][CH:46]([CH3:47])[CH3:48])[CH2:49][OH:50].[n:17]1([O:18][C:19]([N:20]([CH3:21])[CH3:22])=[N+:23]([CH3:24])[CH3:25])[c:26]2[cH:27][cH:28][cH:29][cH:30][c:31]2[n:32][n:33]1>>[Br:1][c:2]1[c:3]([Cl:11])[n:4][cH:5][c:6]([C:7](=[O:9])[NH:43][CH:44]([CH2:45][CH:46]([CH3:47])[CH3:48])[CH2:49][OH:50])[cH:10]1

Participants

6

Reactant 5

HCID 26255TetrafluoroborateHCID 790302-Amino-4-methylpentan-1-olHCID 81531DiisopropylethylamineHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 2854335-Bromo-6-chloropyridine-3-carboxylic acid

Product 1

HCID 911341745-bromo-6-chloro-N-(1-hydroxy-4-methylpentan-2-yl)pyridine-3-carboxamide

Sources & evidence

ORD record
ord-ef541f18f61140df8d6dd5db8804e51c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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