Ethyl chloroformate → N-(1-Methyldecyl)-3-phenyl-3-(3-nitrophenyl)propenamide

HRID 66621Notes

Reaction equation

HRID 66621 reaction equation
[C:1]1([C:7]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)=[CH:8][C:9]([OH:11])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.ClC(OCC)=O.[CH3:27][CH:28]([NH2:38])[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]>>[CH3:27][CH:28]([NH:38][C:9](=[O:11])[CH:8]=[C:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=1)[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]

Participants

4

Reactant 3

HCID 10928Ethyl chloroformateHCID 1144762-UndecanamineHCID 536864243-Phenyl-3-(3-nitrophenyl)propenoic acid

Product 1

HCID 53762315N-(1-Methyldecyl)-3-phenyl-3-(3-nitrophenyl)propenamide

Procedure

The title compound was prepared from 3-phenyl-3-(3-nitrophenyl)propenoic acid via mixed anhydride formation using ethyl chloroformate, followed by reaction with 1-methyldecylamine, substantially according to the procedure of Preparation 21. This gave a 92% yield of an oil.

Workup

  1. customsubstantially according to the procedure of Preparation 21

Sources & evidence

ORD record
ord-e4f5ef47918d4acabaa25bcfb67f94e6
Source dataset
uspto-grants-1982_08
Patent number
US04342781

Reaction notes

Loading…