Methanol → (1-methyl-1H-benzo[d]imidazol-2-yl)(4-(3-morpholinopyrazin-2-yloxy)phenyl)methanone

HRID 666221Notes

Reaction equation

HRID 666221 reaction equation
[C:31](=[O:32])([O-:33])[O-:34].[CH3:44][OH:45].[Cs+:35].[Cs+:36].[I:37][CH3:38].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[nH:1]1[c:2]([C:10](=[O:11])[c:12]2[cH:13][cH:14][c:15]([O:18][c:19]3[n:20][cH:21][cH:22][n:23][c:24]3[N:25]3[CH2:26][CH2:27][O:28][CH2:29][CH2:30]3)[cH:16][cH:17]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[n:1]1([CH3:31])[c:2]([C:10](=[O:11])[c:12]2[cH:13][cH:14][c:15]([O:18][c:19]3[n:20][cH:21][cH:22][n:23][c:24]3[N:25]3[CH2:26][CH2:27][O:28][CH2:29][CH2:30]3)[cH:16][cH:17]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

7

Reactant 6

HCID 887MethanolHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 462079381h-Benzimidazol-2-Yl(4-{[3-(Morpholin-4-Yl)pyrazin-2-Yl]oxy}phenyl)methanone

Product 1

HCID 59351424(1-methyl-1H-benzo[d]imidazol-2-yl)(4-(3-morpholinopyrazin-2-yloxy)phenyl)methanone

Sources & evidence

ORD record
ord-b9687854e90f4c1aa967265a4ecee36e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…