1,4-Dioxane → 5-[(2-Chloro-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)amino]-1-methylpiperidin-2-one

HRID 666268Notes

Reaction equation

HRID 666268 reaction equation
[CH:12]([N:13]([CH:14]([CH3:15])[CH3:16])[CH2:17][CH3:18])([CH3:19])[CH3:20].[Cl:1][c:2]1[n:3][c:4]([Cl:11])[c:5]2[c:6]([n:7]1)[CH2:8][CH2:9][S:10]2.[NH2:21][CH:22]1[CH2:23][CH2:24][C:25](=[O:29])[N:26]([CH3:28])[CH2:27]1.[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1>>[Cl:1][c:2]1[n:3][c:4]([NH:21][CH:22]2[CH2:23][CH2:24][C:25](=[O:29])[N:26]([CH3:28])[CH2:27]2)[c:5]2[c:6]([n:7]1)[CH2:8][CH2:9][S:10]2

Participants

5

Reactant 4

HCID 312751,4-DioxaneHCID 81531DiisopropylethylamineHCID 457899672,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidineHCID 510721765-Amino-1-methylpiperidin-2-one

Product 1

HCID 723642525-[(2-Chloro-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)amino]-1-methylpiperidin-2-one

Sources & evidence

ORD record
ord-dec936b97d0a4ff88a24ad2ef86a6ed7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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