Pyridine → 4-oxo-10-(2-methylpropionamido)-4H-pyrimido[1,2-C]quinazoline-3-carboxylic acid

HRID 666636Notes

Reaction equation

HRID 666636 reaction equation
[I-:26].[Li+:27].[O:1]=[c:2]1[c:3]([C:22](=[O:23])[O:24][CH3:25])[cH:4][n:5][c:6]2[n:7]1[cH:8][n:9][c:10]1[cH:11][cH:12][c:13]([NH:16][C:17]([CH:18]([CH3:19])[CH3:20])=[O:21])[cH:14][c:15]21.[cH:28]1[cH:29][cH:30][n:31][cH:32][cH:33]1>>[O:1]=[c:2]1[c:3]([C:22](=[O:23])[OH:24])[cH:4][n:5][c:6]2[n:7]1[cH:8][n:9][c:10]1[cH:11][cH:12][c:13]([NH:16][C:17]([CH:18]([CH3:19])[CH3:20])=[O:21])[cH:14][c:15]21

Participants

5

Reactant 4

HCID 1049PyridineHCID 28486Lithium ionHCID 30165Iodide IonHCID 13060556methyl 4-oxo-10-(2-methylpropionamido)-4H-pyrimido[1,2-C]quinazoline-3-carboxylate

Product 1

HCID 130605604-oxo-10-(2-methylpropionamido)-4H-pyrimido[1,2-C]quinazoline-3-carboxylic acid

Sources & evidence

ORD record
ord-1c7e852a7eb34741afef9eb0ce7b0618
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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