Dimethyl Sulfoxide → 4-(Benzyloxy)-1-(1-(2,2-dimethoxyethyl)-1H-indazol-5-yl)pyridin-2(1H)-one

HRID 666952Notes

Reaction equation

HRID 666952 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][n:6][n:7]([CH2:11][CH:12]([O:13][CH3:14])[O:15][CH3:16])[c:8]2[cH:9][cH:10]1.[CH2:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[O:24][c:25]1[cH:26][c:27](=[O:31])[nH:28][cH:29][cH:30]1.[CH3:49][S:50]([CH3:51])=[O:52].[Cu:53][I:54].[K+:32].[K+:33].[O-:34][C:35]([O-:36])=[O:37].[OH:38][c:39]1[cH:40][cH:41][cH:42][c:43]2[c:44]1[n:45][cH:46][cH:47][cH:48]2>>[c:2]1(-[n:28]2[c:27](=[O:31])[cH:26][c:25]([O:24][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[cH:30][cH:29]2)[cH:3][c:4]2[cH:5][n:6][n:7]([CH2:11][CH:12]([O:13][CH3:14])[O:15][CH3:16])[c:8]2[cH:9][cH:10]1

Participants

8

Reactant 7

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 19238-HydroxyquinolineHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 36077244-Benzyloxy-2(1H)-pyridoneHCID 592933985-Bromo-1-(2,2-dimethoxyethyl)-1H-indazole

Product 1

HCID 592933874-(Benzyloxy)-1-(1-(2,2-dimethoxyethyl)-1H-indazol-5-yl)pyridin-2(1H)-one

Sources & evidence

ORD record
ord-8318b0ef4f1e4e9fbce24094e082a79d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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