Bicarbonate Ion → tert-butyl N-(7-bromo-2-ethylpyrazolo[1,5-a]pyridin-3-yl)-N-cyclopropylmethylcarbamate
Reaction equation
[Br:35][C:36]([F:37])([F:38])[C:39]([F:40])([F:41])[Br:42].[C:43](=[O:44])([OH:45])[O-:46].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[CH:12]1([CH2:15][N:16]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[c:24]2[c:25]([CH2:33][CH3:34])[n:26][n:27]3[c:28]2[cH:29][cH:30][cH:31][cH:32]3)[CH2:13][CH2:14]1.[Na+:47].[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1>>[CH:12]1([CH2:15][N:16]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[c:24]2[c:25]([CH2:33][CH3:34])[n:26][n:27]3[c:28]2[cH:29][cH:30][cH:31][c:32]3[Br:35])[CH2:13][CH2:14]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9ab917614b0f445abb3778e2bfc9f3da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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