HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 20528962, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 20528919 | HCID 20528919 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Product | HCID 20528962 | HCID 20528962 | — |
Reaction Steps
The 2-amino substituent of Step A product when treated with sodium nitrite as described in Step E of Preparation 81 is converted to the 2-hydroxy group. Treatment of the 2-hydroxy-3-morpholino-6-methopxypyrazine with phosphorus oxychloride by Preparation 13, Step B method, gives 2-chloro-3-morpholino-6-methoxypyrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04343802 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-246a6856eb474f1f861fd9865d10550f |
| Source note | uspto-grants-1982_08 |