Carbonate Ion → 3,4-difluoro-N-(2-methylpyrimidin-5-yl)benzamide

HRID 667513Notes

Reaction equation

HRID 667513 reaction equation
[C:10](=[O:11])([O-:12])[O-:13].[CH3:1][B:2]1[O:3][B:4]([CH3:5])[O:6][B:7]([CH3:8])[O:9]1.[Cl:16][c:17]1[n:18][cH:19][c:20]([NH:23][C:24]([c:25]2[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]2)=[O:33])[cH:21][n:22]1.[Cs+:14].[Cs+:15].[O:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1>>[CH3:10][c:17]1[n:18][cH:19][c:20]([NH:23][C:24]([c:25]2[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]2)=[O:33])[cH:21][n:22]1

Participants

6

Reactant 5

HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 574072TrimethylboroxineHCID 10149311Ica-069673

Product 1

HCID 101927903,4-difluoro-N-(2-methylpyrimidin-5-yl)benzamide

Sources & evidence

ORD record
ord-30d2e8bd996741699b9088c0d130f133
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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