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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66754Generated: October 25, 2026

Phosphorus oxychloride → 2-Chloro-3,5-dimorpholinopyrazine

https://huagongshe.com/reaction/66754

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
Reactant2-Amino-3,5-dimorpholinopyrazineHCID 20528931—
ReactantSodium NitriteHCID 23668193—
Product2-Chloro-3,5-dimorpholinopyrazineHCID 20528990—

Reaction Steps

This product is obtained by treating the 2-amino-3,5-dimorpholinopyrazine with sodium nitrite by the method described in the preceding procedure, Step C, and then with phosphorus oxychloride by the method described in Preparation 13, Step B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04343802
Source datasetuspto-grants-1982_08
ORD IDord-33d1fe42ea6b4301866234e57d234b2a
Source noteuspto-grants-1982_08