Piperidine → 5-Chloro-6-piperidin-1-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([I:18])[c:13]([Cl:17])[cH:14][c:15]2[CH2:16]1.[CH2:19]1[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([N:22]3[CH2:21][CH2:20][CH2:19][CH2:24][CH2:23]3)[c:13]([Cl:17])[cH:14][c:15]2[CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-4c03fe8b441546d3aaa62b51f3dce90c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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