Hydrochloric Acid → 4-[2-(5-Chloro-2-fluoro-phenyl)-6,6-dimethyl-6,7-dihydro-5H-cyclopentapyrimidin-4-ylamino]-nicotinic acid
Reaction equation
[CH3:1][O:2][C:3]([c:4]1[cH:5][n:6][cH:7][cH:8][c:9]1[NH:10][c:11]1[n:12][c:13](-[c:22]2[c:23]([F:29])[cH:24][cH:25][c:26]([Cl:28])[cH:27]2)[n:14][c:15]2[c:16]1[CH2:17][C:18]([CH3:20])([CH3:21])[CH2:19]2)=[O:30].[ClH:33].[Na+:32].[O:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1.[OH-:31]>>[O:2]=[C:3]([c:4]1[cH:5][n:6][cH:7][cH:8][c:9]1[NH:10][c:11]1[n:12][c:13](-[c:22]2[c:23]([F:29])[cH:24][cH:25][c:26]([Cl:28])[cH:27]2)[n:14][c:15]2[c:16]1[CH2:17][C:18]([CH3:20])([CH3:21])[CH2:19]2)[OH:30]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f1cb229562184da2bcc72188db18dd9b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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