1-Pentanol → 4-[1-(6,7-Dimethoxyquinazolin-2-yl)piperidin-4-ylamino]benzoic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([c:7]1[cH:8][cH:9][c:10]([NH:13][CH:14]2[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2)[cH:11][cH:12]1)=[O:20].[CH2:36]([OH:37])[CH2:38][CH2:39][CH2:40][CH3:41].[Cl:21][c:22]1[n:23][c:24]2[cH:25][c:26]([O:34][CH3:35])[c:27]([O:32][CH3:33])[cH:28][c:29]2[cH:30][n:31]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([c:7]1[cH:8][cH:9][c:10]([NH:13][CH:14]2[CH2:15][CH2:16][N:17]([c:22]3[n:23][c:24]4[cH:25][c:26]([O:34][CH3:35])[c:27]([O:32][CH3:33])[cH:28][c:29]4[cH:30][n:31]3)[CH2:18][CH2:19]2)[cH:11][cH:12]1)=[O:20]Participants
4
Sources & evidence
- ORD record
- ord-49160196c1af4c39b8d7e8d6598da701
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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