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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66887Generated: November 1, 2026

Hydrochloric Acid → 2-[7,8-Dihydro-9-(4-pyridyl)-6H-pyrrolo[1,2-a]indole-2-yloxy]-2-methyl-propanoic acid hydrochloride

https://huagongshe.com/reaction/66887

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 54141958HCID 54141958—
Product2-[7,8-Dihydro-9-(4-pyridyl)-6H-pyrrolo[1,2-a]indole-2-yloxy]-2-methyl-propanoic acid hydrochlorideHCID 70548589—

Reaction Steps

The above compound was prepared from 2-[7,8dihydro9-(4-pyridyl)-6H-pyrrolo[1,2-a]indole-2-yloxy]-2-methyl-propanoic acid ethylester by alkaline hydrolysis using a procedure analogous to that of Example 66. When the aqueous alkaline solution was acidified with 2N hydrochloric acid, the hydrochloride precipitated, which was then recrystillzed from ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04343811
Source datasetuspto-grants-1982_08
ORD IDord-c7d2e9142e68488599590cfbc6910a17
Source noteuspto-grants-1982_08