Ethyl formate → 5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine-3-carbaldehyde

HRID 668887Notes

Reaction equation

HRID 668887 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([Cl:7])[c:8]1[CH2:9][O:10][CH:11]1[CH2:12][CH2:13][CH2:14][CH2:15][O:16]1.[CH2:17]([O:18][CH:19]=[O:20])[CH3:21].[Cl:22][c:23]1[c:24]([CH2:34][O:35][CH:36]2[O:37][CH2:38][CH2:39][CH2:40][CH2:41]2)[c:25]([C:29]([CH2:30][O:31][CH3:32])=[O:33])[cH:26][n:27][cH:28]1>>[Cl:22][c:23]1[c:24]([CH2:34][O:35][CH:36]2[O:37][CH2:38][CH2:39][CH2:40][CH2:41]2)[c:25]([CH:29]=[O:33])[cH:26][n:27][cH:28]1

Participants

4

Reactant 3

HCID 8025Ethyl formateHCID 44190473HCID 44190473, compoundHCID 670771431-[5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-yl]-2-methoxy-ethanone

Product 1

HCID 441904745-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine-3-carbaldehyde

Sources & evidence

ORD record
ord-cfb03d53e8d740d7badefb2ea01b0ed4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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