Hydrochloric Acid → 4-[7-[1-(Isopropylsulfonyl)piperidin-4-yl]-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl]-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine

HRID 668931Notes

Reaction equation

HRID 668931 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:8]2[n:9][c:10]([NH2:31])[n:11][c:12]([N:14]3[CH2:15][c:16]4[cH:17][c:18]([CH:25]5[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]5)[cH:19][cH:20][c:21]4[CH2:22][CH:23]3[CH3:24])[cH:13]2)[CH2:6][CH2:7]1.[CH3:33][CH:34]([CH3:35])[S:36](=[O:37])(=[O:38])[Cl:39].[ClH:32]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:8]2[n:9][c:10]([NH2:31])[n:11][c:12]([N:14]3[CH2:15][c:16]4[cH:17][c:18]([CH:25]5[CH2:26][CH2:27][N:28]([S:36]([CH:34]([CH3:33])[CH3:35])(=[O:37])=[O:38])[CH2:29][CH2:30]5)[cH:19][cH:20][c:21]4[CH2:22][CH:23]3[CH3:24])[cH:13]2)[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 824082-Propanesulfonyl chlorideHCID 59402258HCID 59402258, compound

Product 1

HCID 594023054-[7-[1-(Isopropylsulfonyl)piperidin-4-yl]-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl]-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-1ae31089f77f4c6fa6d7010747872714
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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