Tetrahydrofuran → 1-(4-(6-Aminopyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea
Reaction equation
[CH2:68]1[O:69][CH2:70][CH2:71][CH2:72]1.[CH3:30][O:31][c:32]1[cH:33][cH:34][c:35]([CH2:36][NH:37][c:38]2[cH:39][c:40]([O:44][c:45]3[c:46]([F:65])[cH:47][c:48]([NH:51][C:52](=[O:53])[NH:54][C:55]([CH2:56][c:57]4[cH:58][cH:59][c:60]([F:63])[cH:61][cH:62]4)=[O:64])[cH:49][cH:50]3)[n:41][cH:42][n:43]2)[cH:66][cH:67]1.[F:17][c:18]1[cH:19][cH:20][c:21]([CH2:22][C:23]([N:24]=[C:25]=[O:26])=[O:27])[cH:28][cH:29]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[n:8][cH:9][n:10][c:11]([NH2:12])[cH:13]2)[c:14]([F:15])[cH:16]1>>[NH2:37][c:38]1[cH:39][c:40]([O:44][c:45]2[c:46]([F:65])[cH:47][c:48]([NH:51][C:52](=[O:53])[NH:54][C:55]([CH2:56][c:57]3[cH:58][cH:59][c:60]([F:63])[cH:61][cH:62]3)=[O:64])[cH:49][cH:50]2)[n:41][cH:42][n:43]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-aa4ae152043e46f7a4fd67043ebf4537
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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