Methanol → 4-[6-(2-Chloro-4-fluoro-benzoylamino)-pyridin-2-yloxy]-2-methyl-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH3:22])[CH2:10][CH:11]([O:14][c:15]2[n:16][c:17]([NH2:21])[cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH2:41]1[O:42][CH2:43][CH2:44][O:45][CH2:46]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:47][OH:48].[Cl:23][c:24]1[c:25]([C:26](=[O:27])[Cl:28])[cH:29][cH:30][c:31]([F:33])[cH:32]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH3:22])[CH2:10][CH:11]([O:14][c:15]2[n:16][c:17]([NH:21][C:26]([c:25]3[c:24]([Cl:23])[cH:32][c:31]([F:33])[cH:30][cH:29]3)=[O:27])[cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1a33c730388044e884f37b0ec3c16d7b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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