Hydrochloric Acid → 1-[3-Chloro-5-(trifluoromethyl)phenyl]-3-[1-(4,4-difluorocyclohexanecarbonyl)-4-(4-fluorophenyl)pyrrolidin-3-yl]-1,3-dimethylurea
Reaction equation
[Cl:2][c:3]1[cH:4][c:5]([N:13]([C:14](=[O:15])[N:16]([CH3:17])[CH:18]2[CH2:19][NH:20][CH2:21][CH:22]2[c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[CH3:30])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1.[ClH:1].[F:31][C:32]1([F:41])[CH2:33][CH2:34][CH:35]([C:38](=[O:39])[OH:40])[CH2:36][CH2:37]1>>[Cl:2][c:3]1[cH:4][c:5]([N:13]([C:14](=[O:15])[N:16]([CH3:17])[CH:18]2[CH2:19][N:20]([C:38]([CH:35]3[CH2:34][CH2:33][C:32]([F:31])([F:41])[CH2:37][CH2:36]3)=[O:39])[CH2:21][CH:22]2[c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[CH3:30])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-bfead72bd9cf413cb94e06192b0746e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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