Hydrochloric Acid → Iodixanol Impurity 25

HRID 669431Notes

Reaction equation

HRID 669431 reaction equation
[CH2:31]1[CH2:32][O:33]1.[ClH:34].[OH2:35].[OH:1][CH:2]([CH2:3][NH:4][C:5]([c:6]1[c:7]([I:27])[c:8]([C:9](=[O:10])[NH:11][CH2:12][CH:13]([CH2:14][OH:15])[OH:16])[c:17]([I:26])[c:18]([NH:21][C:22]([CH2:23][Cl:24])=[O:25])[c:19]1[I:20])=[O:28])[CH2:29][OH:30]>>[OH:1][CH:2]([CH2:3][NH:4][C:5]([c:6]1[c:7]([I:27])[c:8]([C:9](=[O:10])[NH:11][CH2:12][CH:13]([CH2:14][OH:15])[OH:16])[c:17]([I:26])[c:18]([N:21]([C:22]([CH2:23][Cl:24])=[O:25])[CH2:31][CH2:32][OH:33])[c:19]1[I:20])=[O:28])[CH2:29][OH:30]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 6354Ethylene OxideHCID 111047205-(2-Chloroacetamido)-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide

Product 1

HCID 12082254Iodixanol Impurity 25

Sources & evidence

ORD record
ord-b6168f9d6a1843e9b5b93e0c11ea6a9d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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