Oxalyl chloride → 3-Hydroxy-4-oxo-3-[(trimethylazaniumyl)methyl]pentanoate

Participants

Reaction Steps

To acetyl carnitine hydrochloride (1.2 g; 0.005 moles) oxalyl chloride (2.5 ml; 0.029 moles) was added and the resulting mixture was kept under stirring at room temperature for 2 hours. The mixture was then dried under vacuum, the residue was washed three times with anhydrous ethyl ether, thus obtaining the acid chloride of acetyl carnitine which was used as such in the next step.

Provenance & Evidence